KOREAN HÆMORRHAGIC FEVER IN STAFF IN AN ANIMAL LABORATORY

Autor: Umenai, Takusei, Woo Lee, Pyung, Toyoda, Takayoshi, Yoshinaga, Kaour, Horiuchi, Togo, Wang Lee, Ho, Saito, Takao, Hongo, Michio, Ishida, Nakao
Zdroj: The Lancet; June 1979, Vol. 313 Issue: 8130 p1314-1316, 3p
Abstrakt: In March, 1975, and January, 1978, there were outbreaks of Korean hæmorrhagic fever (K.H.F.) among staff in the animal laboratory of the clinical research building of Tohoku University hospital. 13 doctors and 1 veterinarian had K.H.F., and all except 1 had a mild but typical clinical course. K.H.F. antibody titres were significantly raised in all 14 patients. 12 other doctors working in the same room had no symptoms and no K.H.F. antibody. K.H.F. antibody was also detected in 3 animal technicians who had not been ill, but who had worked in the same room. Antibody was not detected in any of the 4 technicians who worked in different animal rooms in another building. Epidemiological studies suggest that laboratory rats were the source of the infection. High titres of K.H.F. antibody were most common in rats reared in the animal laboratory associated with the outbreak.
Databáze: Supplemental Index