| Autor: |
Hiller, Alma, Clausen, Samuel W., Mosenthal, Herman O. |
| Zdroj: |
Experimental Biology and Medicine; May 1917, Vol. 14 Issue: 8 p170-171, 2p |
| Abstrakt: |
The material for these analyses was obtained at operations for severe lacerations, carcinoma of the breast, or gangrene of the extremities. Only such specimens were utilized as were not involved by the pathological process. This seemed to be the only available source from which muscle tissue that might be regarded as normal could be procured. In every case the blood of these subjects was analyzed for its non-protein nitrogen as well as urea content. Any patients in whom these were above the normal would not have been utilized in this series. As a matter of fact, no abnormal bloods were encountered among these cases.The maximal, minimal and average figures, as well as the number of determinations for each substance, are given in the appended table.The results for the non-protein nitrogen are much lower than they should be. These data were obtained by extracting the muscle tissue by alcohol. Alcohol does not dissolve the kreatin. Since this substance forms such a large portion of the non-protein nitrogen of muscle, a considerable error is introduced. It is our aim in completing this series of determinations to employ trichloracetic acid or some other fluid for extraction which will approximate the true values more closely.It is hoped that these studies may form a basis for comparison with pathological muscle tissue. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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