| Autor: |
Verstraete, M., Brower, R.W., Collen, D., Dunning, A.J., Lubsen, J., Michel, P.L., Schofer, J., Vanhaecke, J., Van De Werf, F., Bleifeld, W., Charbonnier, B., De Bono, D.P., Lennane, R.J., Mathey, D.G., Raynaud, PH., Vahanian, A., Kley, G.A.vande, Essen, R.Von |
| Zdroj: |
The Lancet; November 1985, Vol. 326 Issue: 8462 p965-969, 5p |
| Abstrakt: |
In a double-blind randomised trial 129 patients with first myocardial infarction of less than 6 h duration were allocated to treatment with human recombinant tissue-type plasminogen activator (rt-PA) given intravenously over 90 min, or to placebo infusion. Coronary angiography at the end of this infusion showed that the infarct-related vessel was patent in 61% of 62 assessable coronary angiograms in the rt-PA-treated group compared with 21% in the control group. Treatment with rt-PA was not accompanied by any major complications. In the rt-PA group the circulating fibrinogen level at the end of the catheterisation was 52±29% (mean±SD) of the starting value. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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