CUSHING'S SYNDROME ASSOCIATED WITH A SUPRASELLAR TUMOUR

Autor: Krieger, D. T., Krieger, H. P., Soffer, L. J.
Zdroj: European Journal of Endocrinology; October 1964, Vol. 47 Issue: 2 p185-199, 15p
Abstrakt: A case is described of a roentgenographically confirmed primary suprasellar tumour in a 14 year old Negro boy, who presented with the clinical and laboratory findings of Cushing's syndrome, together with hyperpigmentation, homonymous hemianopia and unilateral ptosis. This appears to be the youngest case exhibiting Cushing's sydrome secondary to this aetiology, and one of a small number in whom the tumour could be well delineated roentgenographically in the presence of an essentially normal sella. The significant endocrine abnormalities were the demonstration of increased plasma corticotrophin levels, and the failure of both pituitary suppression by dexamethasone and of adrenal stimulation by corticotrophin. The tumour was extremely sensitive to 4500 r 60Co therapy. The remission produced thus far is of two years duration.
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