| Autor: |
Milne, J. S., Irons, A. W., Kennedy, G., Wallace, Edith T. |
| Zdroj: |
Scottish Medical Journal; March 1969, Vol. 14 Issue: 3 p76-81, 6p |
| Abstrakt: |
In a general practice an attempt was made to determine the relative merits of cycloserine, sulphadimidine or nitrofurantoin in the treatment of urinary tract infection. Bacteriological follow-up continued for 2years. The incidence of patients with symptoms and with significant bacteriuria before treatment was 13per 1,000females at risk.With a follow-up of 50days nitrofurantoin and cycloserine had an apparent cure rate of 78and 79per cent respectively. Sulphadimidine had a cure rate of only 43per cent due largely to a higher incidence of organisms resistant in vitro. Results after 2years show that apparent cures are much fewer (nitrofurantoin 46%, cycloserine 36%, sulphadimidine 29%) and there is much less difference in the effectiveness of the various drugs. Only 4patients stopped treatment because of drug toxicity.The results of intravenous pyelography in 155patients suggest that rather than X-ray all patients with urinary-tract symptoms, prolonged bacteriological follow-up will reveal those in whom X-rays may be helpful. |
| Databáze: |
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