| Autor: |
TROTMAN, C. N. A., FIDDES, I. J. S., GRUND, E. R., McHANWELL, S., SANDERS, D. J., SANDERSON, CATHERINE, SHAW, B. |
| Zdroj: |
Journal of Endocrinology; January 1976, Vol. 68 Issue: 1 p5-12, 8p |
| Abstrakt: |
Immunoreactive gastrin was measured in subcellular fractions of rat gastric mucosa. The sedimentational properties of subcellular gastrin-containing structures were distinct from those of mitochondria. After centrifugation in sucrose density gradients using a zonal rotor, the peak of immunoreactive gastrin was found in 1·17–1·18 g cm−3density sucrose (1·35 m; 39·5%, w/w). A thermolabile component with 125I-labelled gastrin-binding activity present in gastric mucosal homogenates and fractions was not associated with the gastrin storage vesicles sedimenting in density gradients. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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