| Autor: |
Salvatoni, A., Dunmore, S. J., Morton, J. L., Etienne, A. T., Beloff-Chain, A., Abraham, R. R. |
| Zdroj: |
Journal of Endocrinology; August 1986, Vol. 110 Issue: 2 p303-307, 5p |
| Abstrakt: |
It has been demonstrated that the insulin secretagogue β-cell-trophin, ACTH(22–39), is present in human plasma. The hormone, separated from plasma by affinity chromatography on a corticotrophin-like intermediate-lobe peptide antibody column, behaves similarly to synthetic β-cell-trophin on a gel filtration column and on reverse-phase high-performance liquid chromatography. Sufficient amounts of the hormone were isolated from the plasma of two patients with Nelson's syndrome to demonstrate its biological activity on the perfused rat pancreas.J. Endocr.(1986) 110,303–307 |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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