Bhc-diol as a Photolabile Protecting Group for Aldehydes and Ketones

Autor: Lu, M., Fedoryak, O. D., Moister, B. R., Dore, T. M.
Zdroj: Organic Letters; June 2003, Vol. 5 Issue: 12 p2119-2122, 4p
Abstrakt: 6-Bromo-4-(1,2-dihydroxyethyl)-7-hydroxycoumarin (Bhc-diol) can be used under simulated physiological conditions as a photoremovable protecting group for aldehydes and ketones. The single- and two-photon-induced release of benzaldehyde, piperonal, acetophenone, and cyclohexanone is demonstrated.
Databáze: Supplemental Index