Coxiella burnetiiBlocks Intracellular Interleukin-17 Signaling in Macrophages

Autor: Clemente, Tatiana M., Mulye, Minal, Justis, Anna V., Nallandhighal, Srinivas, Tran, Tuan M., Gilk, Stacey D.
Zdroj: Infection and Immunity; August 2018, Vol. 86 Issue: 10
Abstrakt: Coxiella burnetiiis an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiellatype IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole membrane into the host cytoplasm, where they manipulate a variety of cell processes.
Databáze: Supplemental Index