| Autor: |
Sholiton, Leon J., Hall, Ila L., Werk, Emile E. |
| Zdroj: |
European Journal of Endocrinology; March 1970, Vol. 63 Issue: 3 p512-518, 7p |
| Abstrakt: |
Rat and bovine brain homogenates have been incubated with [4-14C] testosterone under standard conditions. With use of paper chromatography, the extracted metabolites were noted to fall into less polar, iso-polar, and more polar fractions. The components of the iso-polar fraction were separated after acetylation by thin-layer chromatography and the major end-product identified by gas-liquid chromatography and recrystallization to constant specific activity.Rat brain forms a major iso-polar metabolite, allo-tetrahydrotestosterone, and a small amount of tetrahydrotestosterone. Neither of these could be detected in the bovine brain incubates. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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