| Autor: |
Merritt, Janet E., Tomlinson, Stephen, Brown, Barry L. |
| Zdroj: |
European Journal of Endocrinology; September 1984, Vol. 107 Issue: 1 p31-35, 5p |
| Abstrakt: |
Abstract. The effect of flunarizine on the secretion of prolactin from monolayer cultures of normal rat pituitary cells has been determined. Both basal and TRHstimulated secretion were found to be significantly inhibited by micromolar concentrations of flunarizine, whereas depolarization (high K+)-stimulated secretion was virtually unaffected. These results indicate that TRH-stimulated prolactin secretion probably involves calcium influx and that flunarizine may be useful as a probe for particular Ca2+channels. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
