Autor: |
Morishita, Hajime, Higuchi, Kazuhiko, Nakago, Kichijiro, Hashimoto, Tadashi, Mitani, Hiroshi, Mori, Takahide, Oshima, Ichiyo |
Zdroj: |
European Journal of Endocrinology; February 1984, Vol. 105 Issue: 2 p145-148, 4p |
Abstrakt: |
Abstract. Plasma LRH-immunoreactive substance in puerperal women was very low on days 5 and 10 post-partum and significantly increased between days 10 and 20 post-partum, but remained at a similar level on day 30 post-partum, which was significantly lower than that in eumenorrhoeic women on day 8 or 9 of the normal cycle. Although LRH administration did not significantly increase serum FSH on day 11 post-partum, daily injections of LRH from days 5 through 10 post-partum caused a significantly increased secretion of FSH on day 11 post-partum, both basally and in response to LRH. No significant difference was observed in serum oestradiol and Prl levels on day 11 post-partum between the two groups of women with and without LRH pre-treatment. It is concluded that the amount of hypothalamic LRH secretion may be small during the first month post-partum, and low basal FSH and unresponsiveness of the pituitary to LRH observed in the early puerperium may result from hypothalamic hypofunction. |
Databáze: |
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