Experimentally induced sandfly fever and vitamin metabolism in man

Autor: Beisel, William R., Herman, Yaye F., Sauberlich, Howerde E., Herman, Robert H., Bartelloni, Peter J., Canham, John E.
Zdroj: The American Journal of Clinical Nutrition; November 1972, Vol. 25 Issue: 11 p1165-1173, 9p
Abstrakt: Vitamin metabolism was studied throughout the course of experimentally induced sandfly fever. Infected and noninfected control subjects were housed on a closed metabolic ward, fed a standardized amount of liquid diet, and given a constant daily quantity of 14 vitamins. Sandfly fever was of typical severity and duration in these subjects and was accompanied by an anticipated sequence of metabolic and hormonal responses. However, no changes attributable to the illness were detected in serum concentrations of vitamins A, B12, C, or folacin or in the urinary excretion of vitamins B1, B6, or niacin. An increased excretion of urinary riboflavin began coincidentally with the onset of fever and progressed in magnitude during the early convalescent period. The riboflavin losses could be explained by negative nitrogen balance.
Databáze: Supplemental Index