| Autor: |
Dibrov, P.A., Skulachev, V.P., Sokolov, M.V., Verkhovskaya, M.L. |
| Zdroj: |
FEBS Letters; June 1988, Vol. 233 Issue: 2 p355-358, 4p |
| Abstrakt: |
Subcellular vesicles of Vibrio alginolyticushydrolyse ATP and accumulate Na+in an ATP‐dependent fashion. The Na+uptake is (i) strongly stimulated by Δψ‐discharging agents, i.e., the protonophorous uncoupler CCCP or valinomycin +K+and (ii) arrested by DCCD at a concentration strongly inhibiting ATP hydrolysis. Lower concentrations of DCCD stimulate the Na+accumulation supported by ATP hydrolysis as well as by NADH oxidation. It is concluded that there is an electrogenic DCCD‐sensitive Na+‐ATPase in the cytoplasmic membrane of V. alginolyticus. |
| Databáze: |
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