| Autor: |
Khvatova, Elena M., Rubanova, Natalia A., Prudchenko, Igor A., Mikhaleva, Inessa I. |
| Zdroj: |
FEBS Letters; July 1995, Vol. 368 Issue: 2 p367-369, 3p |
| Abstrakt: |
Metabolic effects of delta‐sleep inducing peptide (DSIP) under hypoxia stress were investigated in rats subjected to short‐term hypoxic conditions (about 0.26 Bar). It was found that DSIP partially restricted stress‐induced changes in activity of mitochondrial monoamine oxidase type A (MAO‐A) and serotonin level in rat brain. A number of DSIP analogues was tested and among them there were some compounds with enhanced ability to counteract hypoxia induced changes in MAO‐A activity and serotonin content in comparison with native neuropeptide. |
| Databáze: |
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