| Autor: |
Akhrem, A.A., Kisel, M.A., Kozlov, I.A., Tsybovsky, I.S., Vulfson, E.N. |
| Zdroj: |
FEBS Letters; August 1985, Vol. 187 Issue: 2 p249-252, 4p |
| Abstrakt: |
1,5‐Difluoro‐2,4‐dinitrobenzene completely inhibits F1‐ATPase when it is used at micromolar concentrations and the inhibitor/enzyme molar ratio is equal to 3. The inhibition can be reversed by dithiothreitol treatment. 7‐Chloro‐4‐nitrobenzofurazan treatment of F1‐ATPase does not prevent the reaction of the enzyme with 1,5‐difluoro‐2,4‐dinitrobenzene. The 1,5‐difluoro‐2,4‐dinitrobenzene‐induced inhibition is thought to be a result of the modification of a tyrosine residue with pK9.1. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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