The role of phospholipase A2in lipid peroxidation‐induced fall of membrane potential of rat liver mitochondria

Autor: Gogvadze, V.G., Brustovetsky, N.N., Zhukova, A.A.
Zdroj: FEBS Letters; May 1990, Vol. 264 Issue: 2 p168-170, 3p
Abstrakt: Cumene hydroperoxide (230 μM)‐induced fall of the membrane potential takes place only in Ca2+‐loaded mitochondria. Inhibitor of phospholipase A2, P‐bromphenacyl bromide prevents uncoupling of mitochondria, having no effect on the accumulation of lipid peroxidation products.
Databáze: Supplemental Index