| Autor: |
Shekerdemian, L.S., Bush, A., Lincoln, C., Shore, D.F., Petros, A.J., Redington, A.N. |
| Zdroj: |
Heart; December 1, 1997, Vol. 78 Issue: 6 p587-593, 7p |
| Abstrakt: |
ObjectiveTo investigate the effects of cuirass negative pressure ventilation on the cardiac output of a group of anaesthetised children after occlusion of an asymptomatic persistent arterial duct, and a group of paediatric patients in the early postoperative period following cardiopulmonary bypass.DesignProspective study.SettingThe paediatric intensive care unit and catheter laboratory of a tertiary care centre.Patients16 mechanically ventilated children were studied: seven had undergone surgery for congenital heart disease, and nine cardiac catheterisation for transcatheter occlusion of an isolated asymptomatic persistent arterial duct.InterventionsCardiac output was measured using the direct Fick method during intermittent positive pressure ventilation and again after a short period of negative pressure ventilation. In five of the post- operative patients a third measurement was made following reinstitution of positive pressure ventilation.ResultsNegative pressure ventilation was delivered without complication, with no significant change in systemic arterial oxygen and carbon dioxide tension. The mixed venous saturation increased from 74% to 75.8% in the healthy children, and from 58.9% to 62.3% in the postoperative group. Negative pressure ventilation increased the cardiac index from 4.0 to 4.5 l/min/m2in the healthy children, and from 2.8 to 3.5 l/min/m2in the surgical group. The increase was significantly higher in the postoperative patients (28.1%) than the healthy children (10.8%).ConclusionsWhile offering similar ventilatory efficiency to positive pressure ventilation, cuirass negative pressure ventilation led to a modest improvement in the cardiac output of healthy children, and to a greater increase in postoperative patients. There are important cardiopulmonary interactions in normal children and in children after cardiopulmonary bypass, and by having beneficial effects on these interactions, negative pressure ventilation has haemodynamic advantages over conventional positive pressure ventilation. |
| Databáze: |
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