Vasculitic neuropathy in a patient with inactive treated lepromatous leprosy

Autor: Bowen, J.R.C., Donaghy, M., McDougall, A.C., Morris, J.H., Lucas, S.B.
Zdroj: Journal of Neurology, Neurosurgery, & Psychiatry (JNNP); April 1, 2000, Vol. 68 Issue: 4 p496-500, 5p
Abstrakt: A 46 year old Asian male with previously treated lepromatous leprosy developed a stepwise multifocal sensory disturbance 25 years later. Neurophysiology demonstrated marked deterioration from previous studies. Sural nerve biopsy disclosed a vasculitic process superimposed on inactive lepromatous leprosy. Immunocytochemical stains for mycobacterial antigen showed deposits within nerve and vessel walls. A delayed vasculitic neuropathy precipitated by persisting mycobacterial antigen is proposed.
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