The Molecular Physiology of Sodium- and Proton-Coupled Solute Transporters

Autor: Steel, Angela, Hediger, Matthias A.
Zdroj: Physiology; June 1998, Vol. 13 Issue: 3 p123-131, 9p
Abstrakt: The expression of cloned Na+- and H+-coupled solute transporters in Xenopus laevis oocytes has permitted detailed molecular and biophysical analysis and illuminated unique mechanistic features. The identification of missense mutations in inherited diseases and site-directed mutagenesis studies have enhanced our understanding of their roles in physiological and pathological processes.
Databáze: Supplemental Index