Downregulation of tumor-suppressor gene LHX6in cancer: a systematic review

Autor: Nathalia, Evelyn, Theardy, Madelaine Skolastika, Elvira, Sharleen, Rosellinny, Graciella, Liyanto, Andrew Steven, Utama, Michael Putra, Sumarpo, Anton
Zdroj: Romanian Journal of Internal Medicine; September 2018, Vol. 56 Issue: 3 p135-142, 8p
Abstrakt: Introduction. LIM Homeobox 6 (LHX6)encodes a LIM homeodomain transcription factor, contributes to tissue development and morphogenesis, and is mostly expressed in medial ganglionic eminence and odontogenic mesenchyme. However, it has been reported to play a role in cancer progression. This narrative review summarizes literatures that emphasize the molecular regulation of LHX6in tumorigenesis.
Databáze: Supplemental Index