| Autor: |
Föll, Thomas, Rehbein, Julia, Reiser, Oliver |
| Zdroj: |
Organic Letters; September 2018, Vol. 20 Issue: 18 p5794-5798, 5p |
| Abstrakt: |
The visible-light-mediated activation of vinyl chlorides derived from α-chloro ethyl cinnamates via oxidative quenching of excited photocatalyst fac-Ir(ppy)3is described. Upon photoelectron transfer and chloride extrusion, the corresponding vinyl radical can be efficiently trapped by enol acetates, giving rise to synthetically useful 1,4-dicarbonyl compounds in good to excellent yields. This transformation is distinguished by mild and environmentally benign reaction conditions and can be performed on a multigram scale, in sharp contrast to contrasting α-bromo ethyl cinnamates, which show low conversion under the various conditions applied. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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