Circulating Recombinant Form CRF02_AG in South America

Autor: Carrion, G., Hierholzer, J., Montano, S., Alava, A., Perez, J., Guevara, A., Laguna-Torres, V., Mosquera, C., Russell, K., Cruz, C., Chauca, G., Kochel, T., Birx, D. L., Sanchez, J. L., Carr, J. K.
Zdroj: AIDS Research and Human Retroviruses; April 01, 2003, Vol. 19 Issue: 4 p329-332, 4p
Abstrakt: With the objective of monitoring the distribution of HIV-1 subtypes and circulating recombinant forms (CRFs) in South America, population-based surveillance studies were performed in seven countries. Peripheral blood mononuclear cell, filter paper, fresh blood, and cocultivation samples were collected from HIV-positive patients from Colombia, Ecuador, Peru, Bolivia, Chile, Argentina, and Uruguay, during a 7-year period (1995–2001). DNA was prepared and HIV envelope subtypes were determined by heteroduplex mobility assay and DNA sequencing from 1289 HIV-positive samples. While subtypes B and F were the most commonly observed subtypes, two CRF02_AG strains were detected, in Ecuador. This is the first report of the existence of this CRF in South America.
Databáze: Supplemental Index