| Autor: |
Murra, May, Lützen, Lisbeth, Barut, Aynur, Zbinden, Reinhard, Lund, Marianne, Villesen, Palle, Nørskov-Lauritsen, Niels |
| Zdroj: |
Journal of Clinical Microbiology; April 2018, Vol. 56 Issue: 7 |
| Abstrakt: |
ABSTRACTAggregatibacterspecies are commensal bacteria of human mucosal surfaces that are sometimes involved in serious invasive infections. During the investigation of strains cultured from various clinical specimens, we encountered a coherent group of 10 isolates that could not be allocated to any validly named species by phenotype, mass spectrometry, or partial 16S rRNA gene sequencing. Whole-genome sequencing revealed a phylogenetic cluster related to but separate from Aggregatibacter aphrophilus. The mean in silicoDNA hybridization value for strains of the new cluster versus A. aphrophiluswas 56% (range, 53.7 to 58.0%), whereas the average nucleotide identity was 94.4% (range, 93.9 to 94.8%). The new cluster exhibited aggregative properties typical of the genus Aggregatibacter. Key phenotypic tests for discrimination of the new cluster from validly named Aggregatibacterspecies are alanine-phenylalanine-proline arylamidase, N-acetylglucosamine, and ß-galactosidase. The name Aggregatibacter kilianiiis proposed, with PN_528 (CCUG 70536Tor DSM 105094T) as the type strain. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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