Tandem carbolithiation/cyclization of 2-(3-phenyl-2-propen-1-yl) oxazolines. A novel route to cyclobutane derivatives
| Autor: | Robinson, Ralph P., Cronin, Brian J., Jones, Brian P. |
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| Zdroj: | Tetrahedron Letters; January 1997, Vol. 38 Issue: 49 p8479-8482, 4p |
| Abstrakt: | Reaction of the 2-(3-phenyl-2-propen-1-yl) oxazolines 1and 3with organolithium reagents leads to cyclobutane ring formation by a novel tandem carbolithiation/cyclization sequence. The products (e.g., 2aand 4a) may be hydrolyzed to the corresponding substituted cyclobutanones (e.g., 7and 8). |
| Databáze: | Supplemental Index |
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