An Unusual Non-Radical Phenolic Coupling

Autor: Bell, Natalie V, Bowman, W.Russell, Coe, Paul F, Turner, Andrew T, Whybrow, Del
Zdroj: Tetrahedron Letters; January 1997, Vol. 38 Issue: 14 p2581-2584, 4p
Abstrakt: 4-Substituted-2,6-diiodophenols undergo non-radicalortho-ortho phenolic coupling by an S N2 mechanism with liberation of I 2to yield the corresponding biphenyls. In particular, the ethyl ester of N- acetyl-3,5-diiodotyrosine gives good yields of the corresponding dityrosine analogue 2under mild conditions . © 1997 Published by Elsevier Science Ltd.
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