A simple and convenient route to 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines

Autor: Gaidarova, Elena L, Borisenko, Anatoly A, Chumakov, Taras I, Mel'nikov, Andrey V, Orlov, Ivan S, Grishina, Galina V
Zdroj: Tetrahedron Letters; January 1998, Vol. 39 Issue: 42 p7767-7770, 4p
Abstrakt: A simple and convenient synthetic approach to the new series of 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines 1a-jhas been developed. This was achieved viaa one-pot process combining metalated 4-piperidinonimine alkylation and intramolecular cyclization.
Databáze: Supplemental Index