First aromatic electrophilic iodination reaction on the solid-phase: Iodination of bioactive peptides

Autor:	Arsequell, Gemma, Espuña, Gemma, Valencia, Gregorio, Barluenga, José, Carlón, Raquel Pérez, González, JoséM.
Zdroj:	Tetrahedron Letters; January 1998, Vol. 39 Issue: 40 p7393-7396, 4p
Abstrakt:	Direct iodination of Tyr residues of peptides anchored on solid supports was accomplished, for the first time, by aromatic electrophilic attack of iodonium ions provided by the IPy 2BF 4reagent. Compatibility studies of the iodination with routine solid-phase synthesis protocols are reported.
Databáze:	Supplemental Index
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