A novel synthesis of tert-leucine viaa Leuckart type reaction
| Autor: | Adger, Brian M., Dyer, Ulrich C., Lennon, Ian C., Tiffin, Peter D., Ward, Simon E. |
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| Zdroj: | Tetrahedron Letters; January 1997, Vol. 38 Issue: 12 p2153-2154, 2p |
| Abstrakt: | An efficient synthesis of racemic tert-leucine from trimethylpyruvic acid using a Leuckart type reaction is described. A facile resolution of an intermediate with α-methylbenzylamine allows entry into either (R)-or (S)- tert-leucine. |
| Databáze: | Supplemental Index |
| Externí odkaz: |
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