Synthesis of 2′,3′-dideoxy-3′-hydroxymethylcytidine: A novel hydroformylation route
Autor: | Kaldor, Stephen W., Fritz, James E., Ward, Jeffrey A. |
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Zdroj: | Tetrahedron Letters; January 1997, Vol. 38 Issue: 9 p1509-1510, 2p |
Abstrakt: | 2′,3′-Dideoxy-3′-hydroxymethylcytidine ( 1) has been synthesized via stereoselective Rh-catalyzed hydroformylation of 2′,3′-didehydro-2′,3′-dideoxycytidine 3b. This synthesis incorporates the first successful hydroformylation of a nucleoside olefin. |
Databáze: | Supplemental Index |
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