Synthesis of 2′,3′-dideoxy-3′-hydroxymethylcytidine: A novel hydroformylation route

Autor: Kaldor, Stephen W., Fritz, James E., Ward, Jeffrey A.
Zdroj: Tetrahedron Letters; January 1997, Vol. 38 Issue: 9 p1509-1510, 2p
Abstrakt: 2′,3′-Dideoxy-3′-hydroxymethylcytidine ( 1) has been synthesized via stereoselective Rh-catalyzed hydroformylation of 2′,3′-didehydro-2′,3′-dideoxycytidine 3b. This synthesis incorporates the first successful hydroformylation of a nucleoside olefin.
Databáze: Supplemental Index