| Autor: |
Gopalsamy, Ariamala, Pallai, Peter V. |
| Zdroj: |
Tetrahedron Letters; January 1997, Vol. 38 Issue: 6 p907-910, 4p |
| Abstrakt: |
The Doebner quinoline synthesis has been adopted to solid phase. Acylation of an amino acid coupled to the Rink polystyrene resin with pyruvyl chloride afforded the immobilized amide 11. Further reaction of 11with the preformed Schiff's base 12or aldehyde 3and aniline 2gave, after trifluoroacetic acid cleavage, 2-arylquinoline-4-carboxylic acid amides 14in good yields. |
| Databáze: |
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