New rearranged products from the methylation of 13-oxobaccatin III

Autor: Pinciroli, Vittorio, Ceccarelli, Walter, Fusar-Bassini, Domeico, Menichincheri, Maria, Mongelli, Nicola, Vanotti, Ermes
Zdroj: Tetrahedron Letters; January 1996, Vol. 37 Issue: 52 p9365-9368, 4p
Abstrakt: Treatment of 7-triethylsilyl-13-oxobaccatin III ( 1) with sodium hydride and methyl iodide gave the methylated ten-membered ring compound 2that rearranged, via intramolecular aldol condensation, to unsaturated decalin ring system ( 3, 4, 5). These molecules were characterized by 1D and 2D NMR tecniques.
Databáze: Supplemental Index