Novel nucleosides via intramolecular functionalization of 2,2′-anhydrouridine derivatives

Autor: McGee, Danny P.C., Sebesta, David P., O'Rourke, Sarah S., Martinez, Rogelio L., Jung, Michael E., Pieken, Wolfgang A.
Zdroj: Tetrahedron Letters; January 1996, Vol. 37 Issue: 12 p1995-1998, 4p
Abstrakt: The generation of novel ribonucleoside analogues derived from 2,2′-anhydrouridines by a 3′-hydroxyl directed intramolecular nucleophilic substitution of the 2′-position is described. The methodology allows for the efficient, regio- and stereoselective elaboration of the 2′-position, often under exceptionally mild reaction conditions.
Databáze: Supplemental Index