| Autor: |
Akhtereeva, A. R., Morozova, L. G., Faizullina, R. A., Ivanovskaya, K. A., Pozdeev, O. K., Valeeva, I. Kh., Abdulkhakov, S. R. |
| Zdroj: |
BioNanoScience; September 2018, Vol. 8 Issue: 3 p930-934, 5p |
| Abstrakt: |
Helicobacter pylori(H. pylori) infection is tightly associated with gastrointestinal disorders such as chronic gastritis, peptic ulcer, gastric MALToma, and gastric cancer. Decreased antibiotic susceptibility in H. pyloriis a worldwide problem. Our objective was to determine in vitro antimicrobial susceptibility of H. pyloriisolates obtained from gastric mucosa biopsies of children with H. pylori-associated gastroduodenal diseases using disk-diffusion method. A total 76 biopsy specimens were studied; antibiotic susceptibility was assessed in case of 30 children in whom H. pyloriwas revealed by bacteriology. The maximum resistance of H. pyloriisolates was revealed to clarithromycin with nine resistant isolates (30.0%). The rate of resistance to metronidazole, amoxicillin, furazolidone, tetracycline, and levofloxacin was 23.3, 33.3, 16.7, 25.0, and 16.7%, respectively. Multidrug resistance was detected in 20.0% of H. pyloristrains. The high prevalence of resistance to antibiotics used in eradication therapy is becoming a problem which needs eradication therapy regimen use based on regional H. pyloriresistance rates. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full text from SpringerLink