Ultrastructural Changes Produced in Cultured, Adriamycin-Treated Myocardial Cells1,2

Autor: Necco, Anna, Dasdia, Teresa, Cozzi, Silvia, Ferraguti, Marco
Zdroj: Tumori Journal; September 1976, Vol. 62 Issue: 5 p537-543, 7p
Abstrakt: The ultrastructural evaluation of the early alterations adriamycin-induced on cultured mice heart cells is reported. The major effects are hypertrophy of the sarcoplasmic reticulum and a market increase of the number and total extension of the gap junctions. These findings are discussed in the light of the information available in the literature.
Databáze: Supplemental Index