Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparummalaria in Eastern Myanmar: an observational study of a regional elimination programme

Autor: Landier, Jordi, Parker, Daniel M, Thu, Aung Myint, Lwin, Khin Maung, Delmas, Gilles, Nosten, François H, Andolina, Chiara, Aguas, Ricardo, Ang, Saw Moe, Aung, Ei Phyo, Baw, Naw Baw, Be, Saw Aye, B'Let, Saw, Bluh, Hay, Bonnington, Craig A., Chaumeau, Victor, Chirakiratinant, Miasa, Cho, Win Cho, Christensen, Peter, Corbel, Vincent, Day, Nicholas PJ, Dah, Saw Hsa, Delmas, Gilles, Dhorda, Mehul, Dondorp, Arjen M, Gaudart, Jean, Gornsawun, Gornpan, Haohankhunnatham, Warat, Hla, Saw Kyaw, Hsel, Saw Nay, Htoo, Gay Nay, Htoo, Saw Nay, Imwong, Mallika, John, Saw, Kajeechiwa, Ladda, Kereecharoen, Lily, Kittiphanakun, Praphan, Kittitawee, Keerati, Konghahong, Kamonchanok, Khin, Saw Diamond, Kyaw, Saw Win, Landier, Jordi, Ling, Clare, Lwin, Khin Maung, Lwin, Khine Shwe War, Ma, Naw K' Yin, Marie, Alexandra, Maung, Cynthia, Marta, Ed, Minh, Myo Chit, Miotto, Olivo, Moo, Paw Khu, Moo, Ku Ler, Moo, Merry, Na, Naw Na, Nay, Mar, Nosten, François H., Nosten, Suphak, Nyo, Slight Naw, Oh, Eh Kalu Shwe, Oo, Phu Thit, Oo, Tun Pyit, Parker, Daniel M., Paw, Eh Shee, Phumiya, Choochai, Phyo, Aung Pyae, Pilaseng, Kasiha, Proux, Stéphane, Rakthinthong, Santisuk, Ritwongsakul, Wannee, Salathibuphha, Kloloi, Santirad, Armon, Sawasdichai, Sunisa, von Seidlein, Lorenz, Shee, Paw Wah, Shee, Paw Bway, Tangseefa, Decha, Thu, Aung Myint, Thwin, May Myo, Tun, Saw Win, Wanachaloemlep, Chode, White, Lisa J, White, Nicholas J, Wiladphaingern, Jacher, Win, Saw Nyunt, Yee, Nan Lin, Yuwapan, Daraporn
Zdroj: The Lancet; May 2018, Vol. 391 Issue: 10133 p1916-1926, 11p
Abstrakt: Potentially untreatable Plasmodium falciparummalaria threatens the Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia, and Vietnam suggested that mass drug administration was safe, and when added to provision of early diagnosis and treatment, could reduce the reservoir of P falciparumand interrupts transmission. We examined the effects of a scaled-up programme of this strategy in four townships of eastern Myanmar on the incidence of P falciparummalaria.
Databáze: Supplemental Index