Incorporation of serinol derived acyclic nucleoside analogues into oligonucleotides: Influence on duplex and triplex formation

Autor: Benhida, Rachid, Devys, Michel, Fourrey, Jean-Louis, Lecubin, Florence, Sun, Jian-Sheng
Zdroj: Tetrahedron Letters; August 1998, Vol. 39 Issue: 34 p6167-6170, 4p
Abstrakt: Phosphoramidites 6a-cwere readily prepared by an original route and used to incorporate serinol derived units I–IIIin oligonucleotides which, compared to their natural analogues, exhibited a decreased htbridization capacity for duplex and triplex formation.
Databáze: Supplemental Index