Oophorectomy in Advanced Breast Cancer: Clinical Radiologic Correlations

Autor: Severini, Aldo, Tesoro-Tess, John David, Oriana, Saro, Preda, Ferdinando, Gardani, Gianstefano, Cozzi, Guido
Zdroj: Tumori Journal; June 1982, Vol. 68 Issue: 3 p211-216, 6p
Abstrakt: The radiograms of the chest and skeleton of 49 patients with advanced breast cancer treated with bilateral ovariectomy were reviewed. The modifications in the secondary localizations and/or their appearance after castration were compared with the findings of the clinical examination. Appearance or progression of intrathoracic lesions, like the appearance or progression of osteolytic lesions, corresponded to a progression of the disease in other sites. Osteoblastic evolution of osteolytic lesions and the appearance of osteoblastic lesions in bones undamaged before ovariectomy were signs of a favorable response to therapy. The response of chest and bone metastases is usually rather early, and the first radiographic survey should be performed about 3 months after ovariectomy.
Databáze: Supplemental Index