Autor: |
Kenosi, M., O’Toole, J., Hawkes, G., Hutch, W., Low, E., Wall, M., Boylan, G., Ryan, C., Dempsey, E. |
Zdroj: |
Journal of Perinatology; 20240101, Issue: Preprints p1-7, 7p |
Abstrakt: |
Cerebral oxygenation (rcSO2) monitoring in preterm infants may identify periods of cerebral hypoxia or hyperoxia. We hypothesised that there was a relationship between rcSO2values and short term outcome in infants of GA?32weeks. RcSO2values were recorded for the first 48?h of life using an INVOS monitor with a neonatal sensor. The association between cranial ultrasound scan measured brain injury and rcSO2was assessed. 120 infants were included. Sixty-nine percent (83) of infants had a normal outcome (no IVH, no PVL, and survival at 1 month); less than one-quarter, 22% (26), had low grade IVH 1 or 2 (moderate outcome); and 9% (11) of infants had a severe outcome (IVH?=?3, PVL or died before 1 month age). rcSO2values were lower for infants GA?28weeks when compared with those GA 28–32, p?0.001. There was no difference in absolute rcSO2values between the three outcome groups but a greater degree of cerebral hypoxia was associated with preterm infants who had low grade 1 or 2 IVH. Infants of GA?28 weeks have lower cerebral oxygenation in the first 2 days of life. A greater degree of hypoxia was seen in infants with grade 1 or 2 haemorrhage. Normative ranges need to be gestation specific. |
Databáze: |
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