| Autor: |
Heinemann-Vernaleken, Bernhild, Palmowski, Anja M., Allgayer, Reiner, Ruprecht, Klaus W. |
| Zdroj: |
Graefe's Archive for Clinical and Experimental Ophthalmology; 20010801, Vol. 239 Issue: 8 p556-561, 6p |
| Abstrakt: |
Abstract. Aim: to compare two different resolutions of multifocal electroretinogram recordings (MF-ERG) in patients with age-related macular degeneration (AMD). Patients and methods: in 20 eyes (14 patients) with early or late stages of AMD, MF-ERGs of 8 min duration were recorded using a low and a high resolution. The central 50º of the retina were stimulated by 103 as well as by 241 stimulus elements. Results were compared with one another and with an age-matched control group. Results: when response averages of equal eccentricity were analysed, amplitudes of the MF-ERG differed significantly from normal within the central 40°. This held true for both low (103) and high (241) resolutions. Sixteen of 20 eyes also showed focal retinal dysfunction at both resolutions. In one case, the high resolution MF-ERGs could detect functional deficits that could not be seen with the lower resolution. However, due to a reduced signal-to-noise ratio three high resolution recordings could not be analysed. Conclusion: high resolution MF-ERG seems more sensitive than low resolution MF-ERG. However, the low resolution (103) MF-ERG is recommended for routine application in the clinic because of its better signal-to-noise ratio. |
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