| Autor: |
Parvathaneni, Sai Prathima, Perumgani, Pullaiah C. |
| Zdroj: |
Asian Journal of Organic Chemistry; February 2018, Vol. 7 Issue: 2 p324-327, 4p |
| Abstrakt: |
We describe a copper(I) catalyzed ortho‐chlorination of aromatic compounds via direct C−H activation by using hypervalent iodine reagent 1‐chloro‐1,2‐benziodoxol‐3‐one. This reaction showed high regioselectivity for the monochlorination of the C−H bonds of 2‐phenyl pyridines and was compatible for a wide range of nitrogen‐containing aromatics. Furthermore, the synthesized iodine(III) reagent was highly stable, recyclable, and can be employed in large‐scale syntheses of halo‐heteroarenes. Halogenation: A chlorination reaction using hypervalent iodine(III) reagent 1‐chloro‐1,2‐benziodoxol‐3‐one has been developed. The reaction is regioselective and is applicable to several nitrogen‐containing aromatic compounds. |
| Databáze: |
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