| Autor: |
Goldstein, Ellie J. C., Citron, Diane M., Tyrrell, Kerin L., Leoncio, Eliza, Merriam, C. Vreni |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; November 2017, Vol. 62 Issue: 2 |
| Abstrakt: |
ABSTRACTRelebactam is an important beta-lactamase inhibitor for certain aerobic organisms, but alone it has no antianaerobic activity, with most anaerobes having MICs of ≥32 μg/ml with the exception of a very few strains. There was no enhancement or antagonism of imipenem activity with the addition of relebactam, including activity against imipenem-resistant strains. The relebactam-imipenem combination had excellent overall activity against the anaerobes tested. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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