Abstrakt: |
The toxic factor in cottonseed can be nullified by three apparently unrelated mechanisms: oxidation, combination with soluble iron salts, and destruction by steam autoclaving. Oxidation is of minor importance except where the toxic factor has first been extracted with ethyl ether and is present in the diet in solution in oil. Detoxication with soluble iron salts is demonstrable even when the iron is administered in the drinking water. Ball-milled petroleum ether-extracted cottonseed meal can be detoxified by autoclaving under conditions which are not effective for the original meal. These results were obtained from feeding tests with rats. |