| Autor: |
Soede-Huijbregts, C., Laren, M. van, Hulsbergen, F. B., Raap, J., Lugtenburg, J. |
| Zdroj: |
Journal of Labelled Compounds and Radiopharmaceuticals; 30 October 2001, Vol. 44 Issue: 12 p831-841, 11p |
| Abstrakt: |
Specifically, 15N-enriched L-histidines have been prepared. The labelling methodology involves introduction of labels in its precursor 1-benzyl-5-hydroxy methyl imidazole, which is converted into L-histidine via the Schöllkopf method. The procedure allows the preparation of the intermediates and finally histidine with high 15N enrichment (99%) at each position, in 29% overall yield starting with 15NH4Cl and 56% with KSC15N, respectively. Copyright © 2001 John Wiley & Sons, Ltd. |
| Databáze: |
Supplemental Index |
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