Physiology and patho-physiology of the cardiac transverse tubular system

Autor: Smith, CER, Trafford, AW, Caldwell, JL, Dibb, KM
Zdroj: Current Opinion in Physiology; February 2018, Vol. 1 Issue: 1 p153-160, 8p
Abstrakt: •T-tubules contain key proteins involved in excitation–contraction coupling.•T-tubule density is varied between species and across chambers of the heart.•T-tubules are lost in disease which is associated with contractile dysfunction.•Proteins including AmpII, JPH2 and TCAP regulate the t-tubule network.
Databáze: Supplemental Index