| Autor: |
Fine, Daniel H., Mendieta, Carlos, Barnett, Michael L., Furgang, David, Naini, Ali, Vincent, Jack W. |
| Zdroj: |
Journal of Periodontology; November 1992, Vol. 63 Issue: 11 p897-901, 5p |
| Abstrakt: |
This study investigated the correlationbetween endotoxin levels and the percentage of Gram‐negative bacteria in healthy sites and in periodontitis sites. Twelve healthy adults participated. Each subject provided 3 periodontitis sites with 5 to 8 mm probing depths that bled on gentle probing and 3 healthy sites with sulcus depths of 1 to 3 mm that did not bleed. Clinical examinations and sterile paper point sampling of all study sites were conducted on days 0, 7, and 14, and site‐specific endotoxin levels and percentage of Gram‐negative bacteria were determined. There were significant differences in both endotoxin levels and percentage Gram‐negative bacteria between healthy and periodontitis sites across all 3 sampling periods, but no difference across sampling periods in the healthy sites and the periodontitis sites, respectively. Correlation coefficients revealed a high degree of correlation between site‐specific endotoxin levels and percentage of Gram‐negative organisms. Using a sample dilution of 1 × 104, endotoxin levels differentiated healthy from Periodontitis sites with a specificity of approximately 91% and a sensitivity of approximately 90%. J Periodontol 1992; 63:897–901. |
| Databáze: |
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