| Autor: |
De Soet, Johannes J., Bokhout, Birgitta, Buijs, Jos F., Van Loveren, Cor, De Graaff, Johannes, Prahl-Andersen, Birte |
| Zdroj: |
The Cleft Palate-Craniofacial Journal; September 1998, Vol. 35 Issue: 5 p460-464, 5p |
| Abstrakt: |
Objective The aim of this study was to investigate the transmission of Streptococcus mutans between children with cleft lip and/or palate and their mothers.Design Saliva samples of 21 mother-child pairs were collected and cultured on plates containing a selective growth medium for mutans streptocci. At least five separate colonies of each colony morphotype were isolated. A polymerase chain reaction (PCR) with randomly chosen primers was used to type the isolates.Results The number of morphotypes and PCR types was significantly lower in the children than in the mothers. Significant correlations were found between the number of morphotypes and PCR types, in the children as well as in the mothers. In only 38% of the mother-child pairs were the same PCR types found in mother and child.Conclusions This suggests that S. mutans had been transmitted from mother to child in one-third of the population studied. No correlations were found among the number of colony-forming units, the number of colony-colony-morphotypes, and the number of PCR types of the mothers and transmission. Similar PCR types in mother and child were found significantly more often in children who had more than one PCR type. The results indicate that transmission of S. mutans from mother to child is not frequent in children with oral cleft. This may have consequences for preventive treatment of cleft lip and/or palate children and their mothers. |
| Databáze: |
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