INTRAMUSCULAR 15(S)15 METHYL PGF2αIN THE TREATMENT OF MISSED ABORTION

Autor: Banerjee, SK, Das Gupta, S, Dawn, CS, Mehta, AC, Kanthamani, CR, Krishna, Usha R, Raghavan, KS
Zdroj: Acta Obstetricia et Gynecologica Scandinavica; January 1988, Vol. 67 Issue: Supplement 145 p45-47, 3p
Abstrakt: Intramuscular 15(S)15 methyl PGF2α(Prostin 15M, Upjohn) was used for induction of labour in cases of missed abortion and intra‐uterine fetal death. The patients received premedication to control the gastrointestinal side effects. Prostin 15M was given at a dose of 250 µg every three hours and escalated whenever required. The trial was interrupted in two out of 83 patients. Altogether 75 patients (92.6%) expelled the fetus with the treatment. The mean induction abortion interval was 14.7 hours. The primigravidae had a longer (18.2 hrs) interval than the multigravidae (13.8 hrs). The mean number of episodes of vomiting was 2.9 and of diarrhoea 3.5 per patient and treatment.
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