| Autor: |
Culshaw, Abigail, Ladell, Kristin, Gras, Stephanie, McLaren, James E, Miners, Kelly L, Farenc, Carine, van den Heuvel, Heleen, Gostick, Emma, Dejnirattisai, Wanwisa, Wangteeraprasert, Apirath, Duangchinda, Thaneeya, Chotiyarnwong, Pojchong, Limpitikul, Wannee, Vasanawathana, Sirijitt, Malasit, Prida, Dong, Tao, Rossjohn, Jamie, Mongkolsapaya, Juthathip, Price, David A, Screaton, Gavin R |
| Zdroj: |
Nature Immunology; November 2017, Vol. 18 Issue: 11 p1228-1237, 10p |
| Abstrakt: |
Cross-reactivity to dengue virus serotypes can trigger life-threatening inflammation. Culshaw et al. show that germline-encoded components of dengue-virus-specific TCRs influence antigen engagament and suggest that ‘innate-like’ recognition of the virus might underpin harmful cross-reactivity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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