Inhibition of the oncogenic fusion protein EWS-FLI1 causes G2-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma
| Autor: | Zöllner, Stefan K., Selvanathan, Saravana P., Graham, Garrett T., Commins, Ryan M. T., Hong, Sung Hyeok, Moseley, Eric, Parks, Sydney, Haladyna, Jessica N., Erkizan, Hayriye V., Dirksen, Uta, Hogarty, Michael D., Üren, Aykut, Toretsky, Jeffrey A. |
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| Zdroj: | Science Signaling; October 2017, Vol. 10 Issue: 499 |
| Abstrakt: | A drug sensitizes Ewing’s sarcoma cells to chemotherapy by inducing mitotic arrest and priming the cells for apoptosis. |
| Databáze: | Supplemental Index |
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